COURSE CONTENT

Theoretical background:

• Pathophysiology of haemostasis -Thrombotic states
• Major clinical manifestations of infections -laboratory approach
• Non-specific infections (respiratory, urinary)
• Non-specific infections (CNS, endocarditis)
• Fever of unknown origin
• Other infections (mononuclear syndromes from EBV, CMV, Toxoplasma -AIDS)
• Systemic auto-inflammatory diseases – the model of Familial Mediterranean fever
• Microbial, viral and parasitic infections of the gastrointestinal tract
• Pancreatic diseases
• Diseases of the esophagus
• Specific infections (brucellosis, leishmaniasis, malaria)
• Biliary diseases
• Stomach diseases
• Electrolytic disorders (K+/Na+)
• Pathogenesis – Clinical manifestations of diabetes mellitus
• Diabetic ketoacidosis – Non-keto hyperglycaemic hyperglycaemic state/ hyperosmosis
• Acid-base balance
• Calcium metabolism – Parathyroid disorders
• Thyroid diseases
• Addison’s disease -Cushing’s disease
• Hypothalamus – Pituitary
• Systemic autoimmunity – The systemic lupus erythematosus model
• Systemic autoimmunity – The rheumatoid arthritis model
• Arterial hypertension – Metabolic syndrome
• Antiphospholipid syndrome
• Pilar hypertension – Liver cirrhosis
• Hepatitis B and C diagnostic approach – Hepatocellular carcinoma
• Vasculitis
• Inflammatory diseases of the colon – Colon adenocarcinoma
• Anemias -Algorithmic diagnostic approach

Clinical Practice:

• Haemostasis disorders
• Diagnostic approach to acute fever
• Diagnostic approach to chronic fever
• Diagnostic approach to abdominal pain
• Diabetes mellitus – Complications
• Electrolytic disorders
• Diagnostic approach to endocrine diseases
• Diagnostic approach to autoimmune diseases – Diagnostic approach – Immunological profile
• Arterial hypertension
• Diagnostic approach to icterus
• Diagnostic approach to anaemias and haemostasis disorders.