COURSE CONTENT

Theoretical knowledge:

1. Morphological manifestations of the cellular damage
2. Morphological alterations of the extracellular matrix
3. Acute inflammatory response
4. Healing and regeneration process
5. Chronic inflammation
6. Immunological response
7. Immune defense disorders
8. Infection
9. Atherosclerosis
10. Thrombosis
11. Embolism and infarction
12. Cellular growth and differentiation
13. Neoplasia
14. Carcinogenesis and Carcinogenic agents
15. Carcinogenesis – Molecular pathways
16. Cancer diagnosis

Laboratory experience:

1. Macroscopic examination of surgical samples
2. Selection of tissue areas for microscopic examination
3. Fixation techniques and tissue processing
4. Tissue embedding, microtomes, tissue section mounting on slides
5. Histochemistry, immunohistochemistry and molecular techniques